Trial Profile

Phase I/II Study of Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Status: Not yet recruiting

Phase of Trial: Phase I/II

Latest Information Update: 04 Jul 2025

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At a glance

Drugs Azacitidine (Primary) ; Durvalumab (Primary) ; Carboplatin; Cisplatin; Gemcitabine; Paclitaxel; Pemetrexed
Indications Non-small cell lung cancer
Focus Adverse reactions; Therapeutic Use

29 Jun 2025 Planned initiation date changed from 2 Jul 2025 to 3 Jul 2025.
27 Jun 2025 Planned initiation date changed from 26 Jun 2025 to 2 Jul 2025.
22 Jun 2025 Planned initiation date changed from 19 Jun 2025 to 26 Jun 2025.

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