A Phase 1, Placebo-controlled, Blinded, Dose-escalation Study to Evaluate the Safety and Immunogenicity of mRNAs Encoding HIV Immunogens (eOD-GT8 60mer, Core-g28v2 60mer, N332-GT5 gp151) in Adult Participants Without HIV and in Overall Good Health in South Africa
Latest Information Update: 22 Feb 2026
At a glance
- Drugs EOD-GT8 60mer (Primary)
- Indications HIV infections
- Focus Adverse reactions; Pharmacodynamics
- Acronyms IAVI G004
Most Recent Events
- 15 Jan 2026 Planned primary completion date changed from 30 Oct 2026 to 8 Dec 2026.
- 15 Dec 2025 Planned End Date changed from 19 Dec 2025 to 31 Mar 2027.
- 15 Dec 2025 Planned primary completion date changed from 19 Dec 2025 to 30 Oct 2026.