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A Phase 1, Placebo-controlled, Blinded, Dose-escalation Study to Evaluate the Safety and Immunogenicity of mRNAs Encoding HIV Immunogens (eOD-GT8 60mer, Core-g28v2 60mer, N332-GT5 gp151) in Adult Participants Without HIV and in Overall Good Health in South Africa

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Trial Profile

A Phase 1, Placebo-controlled, Blinded, Dose-escalation Study to Evaluate the Safety and Immunogenicity of mRNAs Encoding HIV Immunogens (eOD-GT8 60mer, Core-g28v2 60mer, N332-GT5 gp151) in Adult Participants Without HIV and in Overall Good Health in South Africa

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 30 May 2025

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At a glance

  • Drugs EOD-GT8 60mer (Primary)
  • Indications HIV infections
  • Focus Adverse reactions; Pharmacodynamics

Most Recent Events

  • 25 May 2025 Planned initiation date changed from 19 Feb 2025 to 9 Sep 2025.
  • 26 Nov 2024 New trial record

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