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A Phase 3b, Open Label, Randomized, standard-of Care Control Arm, Multicenter, Superiority Study Evaluating the Efficacy, Safety, and Tolerability of Injectable CAB LA + RPV LA in Viremic Participants Living With HIV-1 (CROWN)

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Trial Profile

A Phase 3b, Open Label, Randomized, standard-of Care Control Arm, Multicenter, Superiority Study Evaluating the Efficacy, Safety, and Tolerability of Injectable CAB LA + RPV LA in Viremic Participants Living With HIV-1 (CROWN)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 05 Aug 2026

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At a glance

  • Drugs Cabotegravir (Primary) ; Rilpivirine (Primary) ; Antiretrovirals
  • Indications HIV-1 infections
  • Focus Registrational; Therapeutic Use
  • Acronyms CROWN
  • Sponsors ViiV Healthcare

Most Recent Events

  • 29 Jul 2026 Planned End Date changed from 28 Aug 2028 to 8 Jun 2028.
  • 22 Jul 2026 Planned End Date changed from 18 Aug 2028 to 28 Aug 2028.
  • 22 Jul 2026 Status changed from recruiting to active, no longer recruiting.

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