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A Randomized, Double-blind, Single and Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MET233 in Otherwise Healthy Adult Participants With Obesity or Overweight

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Trial Profile

A Randomized, Double-blind, Single and Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MET233 in Otherwise Healthy Adult Participants With Obesity or Overweight

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Mar 2026

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At a glance

  • Drugs MET 233i (Primary)
  • Indications Obesity
  • Focus Adverse reactions
  • Sponsors Metsera; Pfizer

Most Recent Events

  • 27 Feb 2026 Planned primary completion date changed from 4 Feb 2026 to 15 Apr 2026.
  • 20 Jan 2026 Planned End Date changed from 3 Jan 2026 to 15 Apr 2026.
  • 20 Jan 2026 Planned primary completion date changed from 24 Oct 2025 to 4 Feb 2026.

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