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Safety and Effectiveness of Tislelizumab and Platinum-based Chemotherapy Combination With H1 Receptor Antagonist Diphenhydraminein Advanced and Metastatic Non-Small Cell Lung Cancer: A Prospective, Randomized-controlled, Multi-center, Open-label, Phase-III Trial

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Trial Profile

Safety and Effectiveness of Tislelizumab and Platinum-based Chemotherapy Combination With H1 Receptor Antagonist Diphenhydraminein Advanced and Metastatic Non-Small Cell Lung Cancer: A Prospective, Randomized-controlled, Multi-center, Open-label, Phase-III Trial

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 19 Dec 2024

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At a glance

  • Drugs Tislelizumab (Primary) ; Carboplatin; Cisplatin; Diphenhydramine; Paclitaxel; Pemetrexed
  • Indications Adenocarcinoma; Adenosquamous carcinoma; Non-small cell lung cancer
  • Focus Therapeutic Use
  • Most Recent Events

    • 11 Dec 2024 Planned End Date changed from 1 Oct 2027 to 1 Nov 2027.
    • 11 Dec 2024 Planned primary completion date changed from 1 Oct 2026 to 1 Nov 2026.
    • 11 Dec 2024 Planned initiation date changed from 1 Nov 2024 to 1 Dec 2024.

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