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A Pilot Study Evaluating the Toxicity and Clinical Benefit of Mitogen-activated Protein Kinase (MAPK) Pathway Inhibition Combined with Programmed Cell Death-1 Checkpoint Blockade (anti-PD1) for the Treatment of BRAF-altered Pediatric Gliomas

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Trial Profile

A Pilot Study Evaluating the Toxicity and Clinical Benefit of Mitogen-activated Protein Kinase (MAPK) Pathway Inhibition Combined with Programmed Cell Death-1 Checkpoint Blockade (anti-PD1) for the Treatment of BRAF-altered Pediatric Gliomas

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 05 Dec 2024

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At a glance

  • Drugs Dabrafenib (Primary) ; Nivolumab (Primary) ; Trametinib (Primary)
  • Indications Glioma
  • Focus Adverse reactions

    • Most Recent Events

    • 05 Dec 2024 New trial record

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