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A Multicenter, Open-label, Fixed-sequence Study to Evaluate Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast Cancer

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Trial Profile

A Multicenter, Open-label, Fixed-sequence Study to Evaluate Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 09 Jun 2026

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At a glance

  • Drugs Trastuzumab rezetecan (Primary) ; Itraconazole; Ritonavir
  • Indications Advanced breast cancer
  • Focus Pharmacokinetics
  • Sponsors Jiangsu Hengrui Medicine Co.

Most Recent Events

  • 04 Jun 2026 Status changed from recruiting to completed.
  • 27 Mar 2025 Status changed from not yet recruiting to recruiting.
  • 06 Dec 2024 New trial record

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