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A Phase I, Open-label Study to Assess the Absolute Bioavailability of Saruparib (AZD5305) and Absorption, Distribution, Metabolism, and Excretion (ADME) of [14C]-Saruparib ([14C]-AZD5305) in Patients With Advanced Solid Malignancies

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A Phase I, Open-label Study to Assess the Absolute Bioavailability of Saruparib (AZD5305) and Absorption, Distribution, Metabolism, and Excretion (ADME) of [14C]-Saruparib ([14C]-AZD5305) in Patients With Advanced Solid Malignancies

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 22 Jan 2025

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At a glance

  • Drugs Saruparib (Primary) ; Saruparib (Primary)
  • Indications Solid tumours
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 16 Jan 2025 Planned End Date changed from 10 Jun 2026 to 1 Sep 2026.
    • 16 Jan 2025 Planned primary completion date changed from 10 Jun 2026 to 1 Sep 2026.
    • 16 Jan 2025 Planned initiation date changed from 18 Dec 2024 to 3 Mar 2025.

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