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A Phase 1 Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of QTX3544 in Patients With Advanced Solid Tumors With KRAS G12V Mutations

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Trial Profile

A Phase 1 Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of QTX3544 in Patients With Advanced Solid Tumors With KRAS G12V Mutations

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 16 Jan 2025

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At a glance

  • Drugs Cetuximab (Primary) ; QTX 3544 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions
  • Sponsors Quanta Therapeutics

    • Most Recent Events

    • 08 Jan 2025 Planned initiation date changed from 2 Jan 2025 to 14 Jan 2025.
    • 08 Jan 2025 Status changed from not yet recruiting to recruiting.
    • 08 Jan 2025 According to Quanta Therapeutics media release, company announced progress across its pipeline of KRAS-directed drug candidates, including U.S. Food and Drug Administration (FDA) Investigational New Drug (IND) application clearance for QTX3544, an oral G12V-preferring, dual ON/OFF state, multi-KRAS inhibitor, enabling initiation of a Phase 1 clinical trial

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