Trial Profile

An Open Label, Multicenter, Phase 1 Study of the PARP1 Inhibitor M9466 in Combination With Carboplatin and Platinum-based Anticancer Therapy (DDRiver 521)

Status: Withdrawn prior to enrolment

Phase of Trial: Phase I

Latest Information Update: 24 Jun 2025

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At a glance

Drugs Atezolizumab (Primary) ; Carboplatin (Primary) ; Etoposide (Primary) ; HRS-1167 (Primary)
Indications Small cell lung cancer; Solid tumours
Focus Adverse reactions
Acronyms DDRiver 521
Sponsors EMD Serono Research & Development Institute

Most Recent Events

17 Jun 2025 Status changed from not yet recruiting to withdrawn prior to enrolment.
28 Feb 2025 Planned initiation date changed from 6 Jan 2025 to 1 Jul 2025.
10 Dec 2024 New trial record

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