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Phase 2 Study to Evaluate Reduced Dose Chemotherapy in Combination With Anti-PD-1 Therapy as First Line Treatment in Vulnerable or Older Adults (Vulnerable or Age ≥70) With Advanced PD-L1 TPS <50% Non-small Cell Lung Cancer

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Trial Profile

Phase 2 Study to Evaluate Reduced Dose Chemotherapy in Combination With Anti-PD-1 Therapy as First Line Treatment in Vulnerable or Older Adults (Vulnerable or Age ≥70) With Advanced PD-L1 TPS <50% Non-small Cell Lung Cancer

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 22 Jan 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary)
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Adverse reactions
  • Most Recent Events

    • 16 Jan 2025 Planned End Date changed from 30 Apr 2033 to 30 Jul 2033.
    • 16 Jan 2025 Planned primary completion date changed from 30 Apr 2030 to 30 Jul 2030.
    • 16 Jan 2025 Planned initiation date changed from 15 Dec 2024 to 15 Mar 2025.

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