A Phase 1, 4-part, Open-label, Fixed-sequence Study to Evaluate the Effects of Lithium and Valproic Acid on the Single-dose Pharmacokinetics of KarXT and Effects of KarXT on the Single-dose Pharmacokinetics of Lithium and Valproic Acid in Healthy Participants
Latest Information Update: 17 Jun 2025
At a glance
- Drugs Trospium chloride/xanomeline (Primary) ; Lithium; Valproic acid
- Indications Psychotic disorders
- Focus Pharmacokinetics
- Sponsors Karuna Therapeutics
Most Recent Events
- 11 Jun 2025 Planned End Date changed from 26 Apr 2025 to 14 Aug 2025.
- 11 Jun 2025 Planned primary completion date changed from 26 Apr 2025 to 14 Aug 2025.
- 03 Mar 2025 Status changed from not yet recruiting to recruiting.