Trial Profile

Zanubrutinib in Combination with Pola-R-CHP and High-dose Methotrexate in Patients with Secondary CNS Lymphoma

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 16 May 2025

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At a glance

Drugs Zanubrutinib (Primary) ; Cyclophosphamide; Doxorubicin; Methotrexate; Polatuzumab vedotin; Prednisone; Rituximab
Indications B-cell lymphoma; CNS cancer; Diffuse large B cell lymphoma; Lymphoma
Focus Adverse reactions

Most Recent Events

08 May 2025 Planned End Date changed from 31 Mar 2030 to 30 Apr 2030.
08 May 2025 Planned primary completion date changed from 31 Mar 2030 to 30 Apr 2030.
10 Feb 2025 Status changed from not yet recruiting to recruiting.

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