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A Phase I Study of Covalent BTK Inhibitor Zanubrutinib in Combination With a CD3-CD20 Bispecific Antibody Odronextamab in Patients With Richter's Transformation

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Trial Profile

A Phase I Study of Covalent BTK Inhibitor Zanubrutinib in Combination With a CD3-CD20 Bispecific Antibody Odronextamab in Patients With Richter's Transformation

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Jun 2025

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At a glance

  • Drugs Odronextamab (Primary) ; Zanubrutinib (Primary)
  • Indications B-cell lymphoma; Hodgkin's disease; Richter's syndrome
  • Focus Adverse reactions

Most Recent Events

  • 17 Jun 2025 Planned End Date changed from 2 Nov 2026 to 13 Dec 2027.
  • 17 Jun 2025 Planned primary completion date changed from 2 Nov 2026 to 13 Dec 2027.
  • 17 Jun 2025 Status changed from not yet recruiting to recruiting.

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