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Early Phase Study to Evaluate the MEK Inhibitor Selumetinib With the MDM2 Inhibitor APG-115 in Patients With Neurofibromatosis Type 1 and Pre-malignant and Malignant Peripheral Nerve Sheath Tumors

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Trial Profile

Early Phase Study to Evaluate the MEK Inhibitor Selumetinib With the MDM2 Inhibitor APG-115 in Patients With Neurofibromatosis Type 1 and Pre-malignant and Malignant Peripheral Nerve Sheath Tumors

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 Dec 2024

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At a glance

  • Drugs Alrizomadlin (Primary) ; Selumetinib
  • Indications Nerve sheath neoplasms; Neurofibromatosis 1
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms MEKMDM2

    • Most Recent Events

    • 20 Dec 2024 New trial record

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