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A phase 1 clinical trial to determine the maximum tolerated dose (MTD) for three different cycles of AB8939.

Trial Profile

A phase 1 clinical trial to determine the maximum tolerated dose (MTD) for three different cycles of AB8939.

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Nov 2025

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At a glance

  • Drugs AB-8939 (Primary) ; Azacitidine (Primary) ; Venetoclax (Primary)
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use

Most Recent Events

  • 17 Oct 2025 Results presented in an AB Science media release.
  • 14 Oct 2025 trial event According to AB SCIENCE media release, the company will host a virtual conference on Thursday, October 16, 2025 ,to provide an update on the Phase 1 study with AB8939
  • 14 Oct 2025 According to AB SCIENCE media release, this trial has completed first two stages determining the maximum tolerated dose after 3 and 14 consecutive days of monotherapy.The third stage is currently underway evaluating the combination of AB8939 + Venetoclax.

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