Trial Profile

Study of Intratumoral Injections of VLPONC-01 in Head and Neck Cancer

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 29 Jan 2026

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At a glance

Drugs Pembrolizumab (Primary) ; VLPONC 01 (Primary)
Indications Carcinoma; Head and neck cancer; Mouth neoplasm; Squamous cell cancer
Focus Adverse reactions
Sponsors VLP Therapeutics

Most Recent Events

20 Jan 2026 Planned End Date changed from 30 May 2027 to 30 Dec 2027.
20 Jan 2026 Planned primary completion date changed from 30 Mar 2027 to 30 Dec 2027.
02 Oct 2025 Number of treatment arms are decreased from 5 to 4 by the removal of "Experimental: Cohort B (1 x 10^9 viral particles per injection)".

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