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A Nation-wide, Multi-center, Prospective, Randomized, Parallel-group, Open-label, Investigator Initiated Pilot Study to Evaluate Efficacy and Safety of Systemic Corticosteroid Plus Ruxolitinib as First-line Therapy in Patients With New-onset Moderate to Severe Chronic Graft-versus-host Disease

Trial Profile

A Nation-wide, Multi-center, Prospective, Randomized, Parallel-group, Open-label, Investigator Initiated Pilot Study to Evaluate Efficacy and Safety of Systemic Corticosteroid Plus Ruxolitinib as First-line Therapy in Patients With New-onset Moderate to Severe Chronic Graft-versus-host Disease

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 26 Feb 2025

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At a glance

  • Drugs Ruxolitinib (Primary) ; Prednisone
  • Indications Graft-versus-host disease
  • Focus Therapeutic Use
  • Acronyms FRONTJAK-001

Most Recent Events

  • 19 Feb 2025 Planned End Date changed from 29 Feb 2028 to 31 Aug 2029.
  • 19 Feb 2025 Planned primary completion date changed from 28 Feb 2027 to 1 Nov 2027.
  • 19 Feb 2025 Status changed from not yet recruiting to recruiting.

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