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A Phase 1, Multicenter, Open-Label Study of CB-010, a CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP)

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Trial Profile

A Phase 1, Multicenter, Open-Label Study of CB-010, a CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP)

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I

Latest Information Update: 09 Oct 2025

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At a glance

  • Drugs CB-010 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Lupus nephritis; Systemic lupus erythematosus
  • Focus Adverse reactions
  • Acronyms GALLOP
  • Sponsors Caribou Biosciences

Most Recent Events

  • 19 Sep 2025 Planned initiation date changed from 1 Jun 2025 to 1 Dec 2027.
  • 19 Sep 2025 Status changed from not yet recruiting to withdrawn prior to enrolment.
  • 15 May 2025 Planned initiation date changed from 1 May 2025 to 1 Jun 2025.

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