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Evaluating The Efficacy and Safety of MET097, a Fully-Biased, Ultra Long-Acting GLP-1RA, In People With Overweight or Obesity: A Phase 3, Multi-Center Randomized, Controlled Trial (VESPER-4)

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Trial Profile

Evaluating The Efficacy and Safety of MET097, a Fully-Biased, Ultra Long-Acting GLP-1RA, In People With Overweight or Obesity: A Phase 3, Multi-Center Randomized, Controlled Trial (VESPER-4)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 09 Sep 2026

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At a glance

  • Drugs Berobenatide (Primary)
  • Indications Obesity; Overweight
  • Focus Registrational; Therapeutic Use
  • Acronyms VESPER-4
  • Sponsors Metsera

Most Recent Events

  • 03 Aug 2026 Planned number of patients changed from 3501 to 3500.
  • 24 Jul 2026 Status changed from recruiting to active, no longer recruiting.
  • 18 May 2026 Planned number of patients changed from 3500 to 3501.

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