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A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

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Trial Profile

A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Oct 2025

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At a glance

  • Drugs Etakafusp alfa (Primary) ; Tarlatamab (Primary)
  • Indications Small cell lung cancer
  • Focus Adverse reactions
  • Acronyms DeLLphi-311
  • Sponsors Amgen

Most Recent Events

  • 06 Oct 2025 Planned End Date changed from 18 Jan 2031 to 4 Jan 2031.
  • 06 Oct 2025 Planned primary completion date changed from 18 Mar 2028 to 4 Mar 2028.
  • 06 Oct 2025 Status changed from not yet recruiting to recruiting.

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