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A Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Atumelnant in Adult Participants With Classic Congenital Adrenal Hyperplasia (Calm-CAH)

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Trial Profile

A Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Atumelnant in Adult Participants With Classic Congenital Adrenal Hyperplasia (Calm-CAH)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 19 Sep 2025

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At a glance

  • Drugs Atumelnant (Primary)
  • Indications Congenital adrenal hyperplasia
  • Focus Pharmacodynamics; Registrational
  • Acronyms CALM-CAH
  • Sponsors Crinetics Pharmaceuticals

Most Recent Events

  • 07 Aug 2025 According to a Crinetics Pharmaceuticals media release, company expects to initiate the CALM-CAH Phase 3 study in adults with CAH in the second half of 2025.
  • 30 Jun 2025 Status changed from planning to recruiting.
  • 16 Jan 2025 New trial record

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