A Phase 3, Randomized, Double-Masked, Active-Controlled Trial of a Single Intravitreal Injection of 4D-150 in Adults With Macular Neovascularization Secondary to Age-Related Macular Degeneration
Latest Information Update: 14 Dec 2025
At a glance
- Drugs 4D-150 (Primary) ; Aflibercept
- Indications Wet age-related macular degeneration
- Focus Registrational; Therapeutic Use
- Acronyms 4FRONT-2
- Sponsors 4D Molecular Therapeutics
Most Recent Events
- 10 Nov 2025 According to a 4D Molecular Therapeutics media release, 52-week topline data expected in H2 2027
- 06 Nov 2025 According to a 4D Molecular Therapeutics media release, enrollment remains on track to be completed in H2 2026.
- 30 Oct 2025 According to a 4D Molecular Therapeutics media release, APAC clinical sites are expected to open by end of year, with Japan sites expected to open in January 2026.