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RESET-MS: A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T Cells (CABA-201) in Participants With Multiple Sclerosis

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Trial Profile

RESET-MS: A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T Cells (CABA-201) in Participants With Multiple Sclerosis

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I/II

Latest Information Update: 01 Jul 2026

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At a glance

  • Drugs Resecabtagene autoleucel (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Multiple sclerosis
  • Focus Adverse reactions
  • Acronyms RESET-MS
  • Sponsors Cabaletta Bio

Most Recent Events

  • 25 Jun 2026 Status changed from not yet recruiting to withdrawn prior to enrolment.
  • 31 Oct 2025 Planned initiation date changed from 1 Aug 2025 to 1 Jun 2026.
  • 17 Jan 2025 New trial record

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