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A Phase 2b, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Dose-ranging Study Investigating the Efficacy and Safety Profile of KT-621 Administered Orally to Adult Participants With Uncontrolled Moderate to Severe Eosinophilic Asthma

Trial Profile

A Phase 2b, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Dose-ranging Study Investigating the Efficacy and Safety Profile of KT-621 Administered Orally to Adult Participants With Uncontrolled Moderate to Severe Eosinophilic Asthma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Mar 2026

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At a glance

  • Drugs KT 621 (Primary)
  • Indications Asthma
  • Focus Therapeutic Use
  • Acronyms BREADTH
  • Sponsors Kymera Therapeutics

Most Recent Events

  • 29 Jan 2026 According to Kymera Therapeutics media release, first patient has been dosed in this trial.
  • 14 Jan 2026 According to Kymera Therapeutics media release, KT-621 BREADTH Phase 2b trial in asthma initiated, with data expected in late-2027
  • 09 Jan 2026 Status changed from planning to recruiting.

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