ORIENT-31 Regimen (Sintilimab Plus Bevacizumab Plus Platinum-doublet Chemotherapy) in Combination With Stereotactic Radiotherapy in EGFR-mutant Metastatic Non-small Cell Lung Cancer After First-line Third-generation EGFR Tyrosine Kinase Inhibitors (ORBIT Study)
Latest Information Update: 16 Mar 2026
At a glance
- Drugs Bevacizumab (Primary) ; Sintilimab (Primary) ; Pemetrexed
- Indications Non-small cell lung cancer
- Focus Therapeutic Use
- Acronyms ORBIT Study
Most Recent Events
- 11 Mar 2026 Planned primary completion date changed from 1 Dec 2026 to 31 Dec 2026.
- 11 Mar 2026 Status changed from not yet recruiting to recruiting.
- 21 Jan 2025 New trial record