Trial Profile

PSMAcTION: A Phase II/III, Open-label, International, Multicenter, Randomized Study of AAA817 Versus Standard of Care in the Treatment of Adult Participants With PSMA Positive Metastatic Castration-resistant Prostate Cancer Who Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

Status: Recruiting

Phase of Trial: Phase II/III

Latest Information Update: 26 May 2026

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At a glance

20 Feb 2026 Planned number of patients changed from 432 to 443.
03 Nov 2025 Planned End Date changed from 11 Apr 2033 to 19 Jul 2033.
03 Nov 2025 Planned primary completion date changed from 20 Mar 2028 to 27 Jun 2028.

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