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KEYMAKER-U01 Substudy 01I: A Phase 2, Randomized, Umbrella Study With Rolling Arms of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC)

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Trial Profile

KEYMAKER-U01 Substudy 01I: A Phase 2, Randomized, Umbrella Study With Rolling Arms of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC)

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Mar 2025

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At a glance

  • Drugs Ifinatamab deruxtecan (Primary) ; Raludotatug deruxtecan (Primary) ; Docetaxel
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms KEYMAKER-U01 Substudy 01I; Substudy 01I
  • Sponsors Merck Sharp & Dohme

    • Most Recent Events

    • 20 Feb 2025 Planned End Date changed from 13 Mar 2032 to 2 Mar 2032.
    • 20 Feb 2025 Planned primary completion date changed from 13 Sep 2030 to 2 Mar 2032.
    • 20 Feb 2025 Planned initiation date changed from 11 Feb 2025 to 23 May 2025.

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