Trial Profile

A Multicentre, Open-label, Phase I/II Study Investigating the Safety, Tolerability, and Preliminary Efficacy of 225Ac-SSO110 in Participants With Extensive Stage Small Cell Lung Cancer (ES-SCLC) or Merkel Cell Carcinoma (MCC) Receiving Standard of Care (SoC)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 01 Jul 2025

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At a glance

Drugs Actinium-225-satoreotide-Ariceum-Therapeutics (Primary) ; Atezolizumab; Avelumab; Durvalumab; Pembrolizumab; Retifanlimab
Indications Merkel cell carcinoma; Small cell lung cancer
Focus Adverse reactions; Therapeutic Use
Acronyms SANTANA-225
Sponsors Ariceum Therapeutics

01 Jul 2025 Last checked against ClinicalTrials.gov: US National Institutes of Health
25 Jun 2025 Planned initiation date (estimated date of first participant enrollment) changed from 1 Apr 2025 to 1 Jun 2025.
22 Apr 2025 Status changed from planning to recruiting.

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