Trial Profile

An Open-Label, Phase 1b Study to Evaluate Safety, Tolerability & Preliminary Activity of the CTPS1 Inhibitor STP938 in Adult Subjects With High Risk Essential Thrombocythaemia Who Are Resistant to or Intolerant of Hydroxycarbamide Therapy

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 27 Oct 2025

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At a glance

02 Sep 2025 According to a Step Pharma media release, today announced that the first participant has been dosed with dencatistat in a phase 1b clinical trial for essential thrombocythaemia. This trial is being conducted at 12 sites across France and the UK.
09 Jul 2025 Status changed from not yet recruiting to recruiting.
22 May 2025 According to a Step Pharma media release, the study is expected to commence in the first half of 2025

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