Trial Profile

An Open-Label, Multi-Center, Dose Escalation, Confirmation, and Expansion Phase I Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of MRG007 (ARR-217) in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 15 Aug 2026

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At a glance

Drugs MRG 007 (Primary)
Indications Colorectal cancer; Gastrointestinal cancer; Pancreatic cancer; Solid tumours
Focus Adverse reactions; Therapeutic Use
Sponsors Lepu Biopharma; Miracogen

12 Aug 2026 According to an ArriVent BioPharma media release, initial phase 1 dose escalation data for ARR-217 planned to be presented at a future medical conference.
12 Aug 2026 According to an ArriVent BioPharma media release, company has initiated phase 1b dose optimization for ARR-217, in patients with gastrointestinal malignancies, in collaboration with Lepu Biopharma Co, Ltd.
27 Jul 2026 Planned number of patients changed from 405 to 572.

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