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A Phase 1/2a Study to Assess Safety, Tolerability, and Efficacy of [212Pb]Pb-DOTAM-MAM279 in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors

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Trial Profile

A Phase 1/2a Study to Assess Safety, Tolerability, and Efficacy of [212Pb]Pb-DOTAM-MAM279 in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 12 Jan 2026

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At a glance

  • Drugs MP 0712 (Primary)
  • Indications Bladder cancer; Cervical cancer; Gastro-enteropancreatic neuroendocrine tumour; Large cell carcinoma; Neuroendocrine carcinoma; Small cell lung cancer
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Molecular Partners AG

Most Recent Events

  • 09 Jan 2026 Planned End Date changed from 1 Sep 2030 to 1 Sep 2032.
  • 09 Jan 2026 Planned initiation date (estimated date of first patient enrollment) changed from 1 Dec 2025 to 1 Jan 2026.
  • 09 Jan 2026 Status changed from not yet recruiting to recruiting.

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