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SBRT Combined With PD-1 Monoclonal Antibody in Unresectable Colorectal Liver Metastases: A Prospective, Multicenter, Single-arm, Phase II Clinical Study (SPARKLE-L)

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Trial Profile

SBRT Combined With PD-1 Monoclonal Antibody in Unresectable Colorectal Liver Metastases: A Prospective, Multicenter, Single-arm, Phase II Clinical Study (SPARKLE-L)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 06 Jul 2026

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At a glance

  • Drugs Sintilimab (Primary) ; Bevacizumab; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
  • Indications Adenocarcinoma; Colorectal cancer; Liver metastases
  • Focus Therapeutic Use
  • Acronyms SPARKLE-L

Most Recent Events

  • 30 Jun 2026 Planned primary completion date changed from 20 Jan 2026 to 20 Jun 2026.
  • 03 Feb 2025 New trial record

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