A Phase I Study of Lintuzumab-Ac-225 in Combination With Venetoclax and ASTX-727 in Adults With Newly Diagnosed AML
Latest Information Update: 09 May 2025
At a glance
- Drugs Cedazuridine/decitabine (Primary) ; Lintuzumab Ac-225 (Primary) ; Venetoclax (Primary)
- Indications Acute myeloid leukaemia
- Focus Adverse reactions; Therapeutic Use
Most Recent Events
- 02 May 2025 Planned initiation date changed from 30 Apr 2025 to 25 Jul 2025.
- 19 Mar 2025 According to an Actinium Pharmaceuticals media release, company will host a KOL call with Dr. Ehab Atallah, Professor of Medicine at the Medical College of Wisconsin to discuss Actimab-A clinical results to date including recently published long-term survival outcomes and the planned pivotal Phase 2/3 clinical trial in r/r AML and trials to be conducted under Actinium's cooperative research and development agreement (CRADA) with the National Cancer Institute (NCI) along with pipeline update.
- 19 Mar 2025 According to Actinium Pharmaceuticals media release, initial clinical data of this study expected by year-end 2025.