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A Phase 1/2, Open-Label, Dose-Escalation and Expansion First-In-Human Study of ATX-295, an Oral Inhibitor of the Kinesin Motor Protein KIF18A, in Patients With Locally Advanced or Metastatic Solid Tumors, Including High-Grade Serous Ovarian Cancer

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Trial Profile

A Phase 1/2, Open-Label, Dose-Escalation and Expansion First-In-Human Study of ATX-295, an Oral Inhibitor of the Kinesin Motor Protein KIF18A, in Patients With Locally Advanced or Metastatic Solid Tumors, Including High-Grade Serous Ovarian Cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Jun 2025

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At a glance

  • Drugs ATX 295 (Primary)
  • Indications Ovarian cancer
  • Focus Adverse reactions; First in man
  • Sponsors Accent Therapeutics

Most Recent Events

  • 03 Apr 2025 Status changed from not yet recruiting to recruiting.
  • 05 Feb 2025 New trial record

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