Trial Profile

Phase 1 Clinical trial assessing safety and efficacy of paxalisib in combination with KEYTRUDA® (pembrolizumab) or LYNPARZA® (olaparib) in women with triple negative breast cancer.

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 16 Feb 2026

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At a glance

Drugs Paxalisib (Primary) ; Carboplatin; Gemcitabine; Olaparib; Paclitaxel; Pembrolizumab
Indications Advanced breast cancer; Triple negative breast cancer
Focus Adverse reactions
Acronyms ABC-Pax

27 Jan 2026 Results published in the Media Release
09 Jan 2026 According to Kazia therapeutics media release, the company expects to provide a clinical and translational update before the end of the month from its ongoing Phase 1b trial evaluating paxalisib in advanced triple-negative breast cancer (TNBC).
10 Dec 2025 According to Kazia therapeutics media release, early clinical data from this 1st patient will be presented in a poster session at the 2025 San Antonio Breast Cancer Symposium (SABCS).

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