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A Single-arm Exploratory Study of the Efficacy and Safety of CDK4/6 Inhibitors in Combination with Endocrine Therapy in the Neoadjuvant Treatment of HR+/HER2- Early Breast Cancer

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Trial Profile

A Single-arm Exploratory Study of the Efficacy and Safety of CDK4/6 Inhibitors in Combination with Endocrine Therapy in the Neoadjuvant Treatment of HR+/HER2- Early Breast Cancer

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 21 Mar 2025

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At a glance

  • Drugs Abemaciclib (Primary) ; Anastrozole (Primary) ; Dalpiciclib (Primary) ; Esomeprazole (Primary) ; Letrozole (Primary) ; Palbociclib (Primary) ; Ribociclib (Primary)
  • Indications Early breast cancer; HER2 negative breast cancer; Male breast cancer
  • Focus Therapeutic Use

Most Recent Events

  • 17 Mar 2025 Planned initiation date changed from 1 Feb 2025 to 1 Apr 2025.
  • 12 Feb 2025 New trial record

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