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A Phase 1, Single-center, Open-label, Non-randomized, Fixed-sequence, Drug-drug Interaction Study to Assess the Effect of Repeated Doses of Intravenous Ceftobiprole on the Pharmacokinetics of Oral Pitavastatin (OATP1B Substrate) and on Plasma Levels of Coproporphyrin I (OATP1B Biomarker) in Healthy Subjects

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A Phase 1, Single-center, Open-label, Non-randomized, Fixed-sequence, Drug-drug Interaction Study to Assess the Effect of Repeated Doses of Intravenous Ceftobiprole on the Pharmacokinetics of Oral Pitavastatin (OATP1B Substrate) and on Plasma Levels of Coproporphyrin I (OATP1B Biomarker) in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Mar 2025

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At a glance

  • Drugs Ceftobiprole (Primary) ; Pitavastatin (Primary)
  • Indications Methicillin-resistant Staphylococcus aureus infections
  • Focus Biomarker; Pharmacokinetics
  • Sponsors Basilea Pharmaceutica

    • Most Recent Events

    • 04 Mar 2025 Status changed from recruiting to completed.
    • 13 Feb 2025 New trial record

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