Trial Profile

A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Atherosclerotic Cardiovascular Disease (ASCVD), and Elevated LDL-C and Lp(a)

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 30 Jun 2025

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At a glance

Drugs Pelacarsen (Primary) ; Inclisiran
Indications Cerebrovascular disorders; Coronary disorders; Peripheral arterial disorders
Focus Registrational; Therapeutic Use
Acronyms ADD-VANTAGE
Sponsors Novartis Pharmaceuticals

24 Jun 2025 Planned End Date changed from 17 Dec 2027 to1 Dec 2027.
24 Jun 2025 Planned primary completion date changed from 27 Aug 2027 to 5 Nov 2027.
24 Jun 2025 Status changed from not yet recruiting to recruiting.

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