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An Open-Label Phase 2a Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients with Dementia with Lewy Bodies (DLB)

Trial Profile

An Open-Label Phase 2a Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients with Dementia with Lewy Bodies (DLB)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Mar 2025

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At a glance

  • Drugs Neflamapimod (Primary)
  • Indications Dementia; Lewy body disease
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors EIP Pharma

Most Recent Events

  • 17 Mar 2025 According to the CervoMed media release, Initial safety, biomarker and pharmacokinetic data from an ongoing trial in patients with being treated with a twice daily regimen (80mg BID) of neflamapimod is expected to be available in the fourth quarter of 2025.
  • 07 Mar 2025 The protocol has been Amended to change the primary endpoint and hence the overall trial focus has also been changed to AR and PK. Indication has also been changed.
  • 14 Feb 2025 New trial record

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