Trial Profile

A Phase 1, Open-Label, Multicenter Study of INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 25 Sep 2025

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At a glance

Drugs INCB 186748 (Primary) ; Cetuximab
Indications Adenocarcinoma; Pancreatic ductal carcinoma; Solid tumours
Focus Adverse reactions
Sponsors Incyte Corporation

Most Recent Events

22 Sep 2025 Status changed from recruiting to active, no longer recruiting.
29 Jul 2025 According to Incyte media release, initial proof of concept data is anticipated in 2H 2025.
03 Apr 2025 Status changed from not yet recruiting to recruiting.

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