Trial Profile

A Phase II Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed or Refractory CD10-Negative Diffuse Large B-Cell Lymphoma (DLBCL) and High-Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements (HGBCL-DH-BCL2)

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 12 Sep 2026

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At a glance

Drugs Ibrutinib (Primary) ; Lenalidomide (Primary) ; Obinutuzumab (Primary) ; Prednisone (Primary) ; Venetoclax (Primary)
Indications B-cell lymphoma; Diffuse large B cell lymphoma
Focus Therapeutic Use

28 Aug 2026 Planned End Date changed from 1 Sep 2027 to 1 Sep 2028.
28 Aug 2026 Planned primary completion date changed from 1 Sep 2027 to 1 Sep 2028.
10 Jul 2025 Planned initiation date (estimated date of first patient enrollment) changed from 7 Jul 2025 to 21 Mar 2026.

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