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A Phase I, Open-label, Multicenter, Dose-Escalating Study to Evaluate the Safety and Tolerability of KH658 Gene Therapy in Participants with Neovascular Age-related Macular Degeneration

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Trial Profile

A Phase I, Open-label, Multicenter, Dose-Escalating Study to Evaluate the Safety and Tolerability of KH658 Gene Therapy in Participants with Neovascular Age-related Macular Degeneration

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 08 May 2025

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At a glance

  • Drugs KH 658 (Primary)
  • Indications Age-related macular degeneration
  • Focus Adverse reactions
  • Acronyms VAN-2401
  • Sponsors Chengdu Origen Biotechnology

Most Recent Events

  • 02 May 2025 Status changed from not yet recruiting to recruiting, according to the Chengdu Origen Biotechnology Media Release.
  • 02 May 2025 According to the Chengdu Origen Biotechnology Media Release, Mark Barakat, M.D. is principal investigator of this study.
  • 02 May 2025 According to the Chengdu Origen Biotechnology Media Release, first patient dosed in this study.

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