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A Phase 1b Study of Tazemetostat in Combination With Zanubrutinib and Anti-CD20 Monoclonal Antibody in Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphomas

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Trial Profile

A Phase 1b Study of Tazemetostat in Combination With Zanubrutinib and Anti-CD20 Monoclonal Antibody in Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphomas

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 14 May 2025

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At a glance

  • Drugs Tazemetostat (Primary) ; Zanubrutinib (Primary) ; Obinutuzumab; Rituximab
  • Indications Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions

Most Recent Events

  • 07 May 2025 Planned initiation date changed from 1 Apr 2025 to 1 Jun 2025.
  • 10 Apr 2025 Planned initiation date changed from 1 Mar 2025 to 1 Apr 2025.
  • 21 Feb 2025 New trial record

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