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Proof of Principle Study Evaluating Single Dose Dual Immune Checkpoint Inhibitors to Increase Intra-tumoral T Cells in Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinomas With ARID1A Mutations: ESR-22-22082

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Trial Profile

Proof of Principle Study Evaluating Single Dose Dual Immune Checkpoint Inhibitors to Increase Intra-tumoral T Cells in Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinomas With ARID1A Mutations: ESR-22-22082

Status: Not yet recruiting
Phase of Trial: Phase 0

Latest Information Update: 13 Jun 2025

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At a glance

  • Drugs Durvalumab (Primary) ; Tremelimumab (Primary)
  • Indications Adenocarcinoma; Gastric cancer; Gastrointestinal cancer; Oesophageal cancer; Solid tumours
  • Focus Therapeutic Use

Most Recent Events

  • 08 Jun 2025 Planned initiation date changed from 1 May 2025 to 1 Aug 2025.
  • 31 May 2025 Planned initiation date changed from 1 Mar 2025 to 1 May 2025.
  • 21 Feb 2025 New trial record

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