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A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of a Multiple Dose Regimen of REGN5381, an NPR1 Monoclonal Antibody Agonist, in Participants With Uncontrolled Hypertension

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Trial Profile

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of a Multiple Dose Regimen of REGN5381, an NPR1 Monoclonal Antibody Agonist, in Participants With Uncontrolled Hypertension

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 10 May 2025

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At a glance

  • Drugs REGN 5381 (Primary)
  • Indications Hypertension
  • Focus Therapeutic Use
  • Acronyms NATRIX-SBP
  • Sponsors Regeneron Pharmaceuticals

Most Recent Events

  • 10 May 2025 Last checked against ClinicalTrials.gov: US National Institutes of Health
  • 29 Apr 2025 Status changed from not yet recruiting to recruiting.
  • 25 Feb 2025 New trial record

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