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First-line Immunotherapy-based Standard of Care and Local Ablative Treatments for Oligometastatic Non-small Cell Lung Cancer Patients: a Randomized, Multicentre, Open-label Phase III Study

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Trial Profile

First-line Immunotherapy-based Standard of Care and Local Ablative Treatments for Oligometastatic Non-small Cell Lung Cancer Patients: a Randomized, Multicentre, Open-label Phase III Study

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 26 Sep 2025

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At a glance

  • Drugs Atezolizumab (Primary) ; Cemiplimab (Primary) ; Pembrolizumab (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms OliGRAIL

Most Recent Events

  • 26 Aug 2025 Planned initiation date changed (estimated date for first patient recruitment) from 1 Jun 2025 to 9 Sep 2025.
  • 22 Jun 2025 Planned initiation date changed from 1 May 2025 to 1 Jun 2025.
  • 13 May 2025 Planned primary completion date changed from 28 Feb 2025 to 1 Feb 2030.

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