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A Phase 1b Clinical Study of NXP900 in Combination With Osimertinib in Subjects With Advanced, EGFRMut+ Non-Small Cell Lung Cancer

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Trial Profile

A Phase 1b Clinical Study of NXP900 in Combination With Osimertinib in Subjects With Advanced, EGFRMut+ Non-Small Cell Lung Cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Feb 2026

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At a glance

  • Drugs NXP 900 (Primary) ; Osimertinib (Primary)
  • Indications Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Nuvectis Pharma

Most Recent Events

  • 11 Feb 2026 According to Nuvectis Pharma media release, the company expects a data readout in 2026.
  • 25 Nov 2025 According to Nuvectis Pharma media release, the company will host a virtual Key Opinion Leader Meeting on Tuesday, December 2, 2025 at 8:00 AM ET to discuss the NXP900 Phase 1b Program in Advanced Solid Tumors, including the combination with osimertinib in non-small cell lung cancer.
  • 11 Aug 2025 According to Nuvectis Pharma media release, The Phase 1b program was initiated following the successful completion of a dose escalation study in patients with advanced solid tumors and a clinical drug-drug interaction study in healthy volunteer, and is intended to include a single agent component, which is now underway, and a combination component that is expected to commence later this year.

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