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A Phase Ib trial evaluating NXP900 as monotherapy in YES1/SRC-driven solid tumors, and in combination with EGFR and ALK inhibitors, in patients with non-small cell lung cancer

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Trial Profile

A Phase Ib trial evaluating NXP900 as monotherapy in YES1/SRC-driven solid tumors, and in combination with EGFR and ALK inhibitors, in patients with non-small cell lung cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 09 Oct 2025

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At a glance

  • Drugs Anaplastic lymphoma kinase inhibitors (Primary) ; Epidermal growth factor receptor antagonists (Primary) ; NXP 900 (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions

Most Recent Events

  • 11 Aug 2025 According to Nuvectis Pharma media release, The Phase 1b program was initiated following the successful completion of a dose escalation study in patients with advanced solid tumors and a clinical drug-drug interaction study in healthy volunteer, and is intended to include a single agent component, which is now underway, and a combination component that is expected to commence later this year.
  • 11 Aug 2025 Status changed from planning to recruiting. as per Nuvectis Pharma media release.
  • 11 Aug 2025 According to Nuvectis Pharma media release, the company will host a conference call on August 12 at 8:30 AM ET to discuss the elements of the Phase 1b program and the overall market opportunity for NXP900.

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