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Escalated Inpatient Ramp-Up of Sonrotoclax in Patients With Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), and Mantle Cell Lymphoma (MCL) (SONIC Study)

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Trial Profile

Escalated Inpatient Ramp-Up of Sonrotoclax in Patients With Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), and Mantle Cell Lymphoma (MCL) (SONIC Study)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Jun 2025

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At a glance

  • Drugs Rituximab (Primary) ; Rituximab (Primary) ; Sonrotoclax (Primary) ; Zanubrutinib (Primary)
  • Indications Chronic lymphocytic leukaemia; Mantle-cell lymphoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 31 May 2025 Planned initiation date changed from 1 Jun 2025 to 1 Jul 2025.
  • 07 May 2025 According BeiGene media release, data readout anticipated in 2H 2025.
  • 25 Apr 2025 Planned initiation date (estimated date of first participant enrollment) changed from 1 Jul 2025 to 1 Jun 2025.

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